CBD Side Effects & Potential Interactions with Medication

by | Mar 7, 2023

CBD, or cannabidiol, has been a hot topic in the wellness industry in recent years due to its potential therapeutic benefits. Derived from the cannabis plant, CBD is often marketed as a natural remedy for a variety of health concerns, including anxiety, chronic pain, and sleep disorders. However, as with any supplement or medication, it is important to understand the potential risks and side effects associated with its use. In particular, CBD can interact with other medications and cause adverse reactions in some individuals. In this post, we will explore some of the potential interactions, common side effects, and general information about what you should be aware of when considering a CBD supplement.

Side Effects of CBD

Although CBD is considered safe and well-tolerated, some users may experience side effects with consumption. Moreover, these effects may vary depending on factors such as individual sensitivity, dosage, and frequency of use. Some common side effects reported by CBD users include:


Some users may feel drowsy or fatigued after consuming CBD. This effect may be due to the calming and relaxation properties of the compound, which are beneficial for people suffering from anxiety or insomnia.


Some individuals may experience diarrhea when using CBD products, especially if they consume high doses. This side effect is more common when users take CBD oil as opposed to other formulations like gummies or creams.

Appetite Changes

CBD may increase or decrease appetite, depending on the individual. For instance, some people may find that their hunger increases, while others may experience a decrease in appetite.

Dry Mouth

CBD can cause a sensation of dryness in the mouth, which may lead to increased thirst.

Possible Drug Interactions

CBD can interact with some prescription and over-the-counter medications, affecting how your body processes these drugs. To avoid potential risks, it is crucial to consult with a healthcare professional before using CBD products if you are taking other medications. Some medications that may interact with CBD include:

Blood Thinners

CBD can increase the levels of blood-thinning medications, such as warfarin, in your bloodstream. This interaction may increase the risk of uncontrolled bleeding or bruising.

Sedatives and Antidepressants

If you are taking sedatives or medications for anxiety or depression, using CBD may amplify their effects, causing excessive sedation or drowsiness.

Epilepsy Medications

CBD may affect the levels of certain anti-epileptic drugs, such as clobazam or valproic acid. This interaction may lead to increased side effects or reduced effectiveness of the medication.

HIV Antivirals

CBD use may alter the blood concentrations of some HIV antiviral medications, which could potentially affect their efficacy.


When taken with CBD, beta-blockers (used to treat high blood pressure) may cause a reduction in heart rate or blood pressure, leading to increased side effects like dizziness or fainting.

Final Word

Are you looking to explore the potential health benefits of CBD products from Muddy Boot Botanicals? While there are a plethora of benefits to be reaped, it’s crucial to understand that there may be some side effects and interactions with medications. It’s always best to consult with a healthcare professional before incorporating CBD into your routine, especially if you’re taking any prescription or over-the-counter medications.

Muddy Boot Botanicals is dedicated to offering high-quality, all-natural CBD products at an incredible value. To ensure the highest quality, we extract and refine our CBD oil in the Pacific Northwest and Colorado. We also go above and beyond by analyzing all externally sourced products using High-Performance Liquid Chromatography and conducting third-party testing in a DEA-certified, accredited laboratory. These tests cover everything from cannabinoid potency to microbial growth, giving you the peace of mind that you’re getting a safe and effective product. Want to see for yourself? Check out the most recent lab results available for each product on our website!

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